Google is changing how Chrome extensions work and the popular uBlock Origin will stop working on Chrome soon so here is two alternatives.
ADBLOCK PLUS
AdBlock Plus is probably the most popular ad-blocking extension for Chrome, It’s been going for over 20 years, and it has one of the best setups for comprehensively blocking advertising across the web. This extension has all the basics covered, including an allow list that lets certain websites display ads by default, the ability to subscribe to public lists of blocked domains, and the ability to block advertising cookies and other background trackers. AdBlock Plus has already been updated to be compliant with Manifest V3.
ADGUARD
AdGuard is my favorite, because it’s easy to set up an reverse allow list. This lets toggle ad blocking on only for websites that are particularly sketchy or annoying. It’s particularly effective on YouTube. AdGuard will flat-out refuse to connect to websites known to maliciously mount phishing attacks or spread malware, and it’s good at collapsing the elements of the page that normally display ads, making formatting much less cluttered. AdGuard’s Manifest V3 is currently in beta testing and it should be transitioning into the primary extension long before the time it becomes mandatory.